和佐 勝史Masafumi Wasa

研究科長  /教授:和佐 勝史



研究科長 /教授
医学博士(大阪大学)/日本小児外科学会名誉指導医/日本外科代謝栄養学会 教育指導医


1981年 大阪大学医学部医学科卒、1983年 大阪府立病院医員(消化器外科)、1991年 大阪大学助手(小児外科)、1993年 米国ハーバード大学マサチューセッツ総合病院研究員、2000年 大阪大学助教授(小児外科)、2007年 大阪大学准教授(医学科教育センター)、2014年 大阪大学教授(医学科教育センター)、大阪大学医学部附属病院卒後教育開発センター長、2020年 滋慶医療科学大学大学院教授、大阪大学名誉教授




  • Kamata S, Yonekura T, Wasa M, Okada A: Nutritional management in hepatic failure: effects of branched chain amino acids enriched amino acid solution on the plasma levels of amino acids and trace amines. In: Tanaka T, Okada A (eds.): Nutritional Support in Organ Failure, pp 277-285, Elsevier Science, Amsterdam, 1990.
  • Yoshida H, Sando K, Wasa M, Takagi Y, Okada A: Home nutritional management - Management of enteral and parenteral nutrition. Asian Medical Journal 42: 335-341, 1999
  • Okada A, Hasegawa T, Wasa M, Azuma T: Small bowel transplantation as a final treatment for intestinal failure. In: Kitajima M, Shimazu M (eds): Current Issues in Liver and Small Bowel Transplantation, pp 115-121, Springer-Verlag Telos, 2002
  • Nakajima K, Wasa M, Nishida T: The Training of Registrars & Residents in Japan. In: Saltzman P.D. (eds.): Best Practices in Surgical Education, pp 1-28, Ethicon Endo-Surgery Inc., 2008.
  • 和佐勝史:日本外科代謝栄養学会におけるアミノ酸研究の歴史. 外科と代謝・栄養 44(1): 57-58, 2010
  • 和佐勝史: 外科診療におけるチーム医療の現況と展望「NSTによる栄養サポート」日本外科学会雑誌 118 (2): 168-172, 2017


  • Wasa M, Bode BP, Abcouwer SF, Collins CL, Tanabe KK, Souba WW: Glutamine as a regulator of DNA and protein biosynthesis in human solid tumor cell lines. Ann Surg 224(2): 189-197, 1996
  • Wasa M, Bode BP, Souba WW: Adaptive regulation of amino acid transport in nutrient-deprived human hepatomas. Am J Surg 171(1): 163-169, 1996
  • Wasa M, Abcouwer SF, Bode BP, Souba WW, Tanabe KK: Effect of adaptation to low glutamine concentrations on cancer growth. Surgical Forum 47: 538-541, 1996
  • Collins CL, Wasa M, Souba WW, Abcouwer SF: Regulation of glutamine synthetase in human brest carcinoma cells and experimental tumors. Surgery 122(2): 451-464, 1997
  • Collins CL, Wasa M, Souba WW, Abcouwer SF: Determination of glutamine dependence and utilization by normal and tumor-derived breast cell lines. J Cell Physiol 176(1): 166-178, 1998
  • Wasa M, Takagi Y, Sando K, Harada T, Okada A: Intestinal adaptation in pediatric patients with short bowel syndrome. Eur J Pediatr Surg 9(4): 207-209, 1999
  • Wasa M, Takagi Y, Sando K, Harada T, Okada A: Long-term outcome of short bowel syndrome in adult and pediatric patients. JPEN-J Parenter Enteral Nutr 23(5): S110-112, 1999
  • Wasa M, Wang HS, Tazuke Y, Okada A: Insulin-like growth factor-I stimulates amino acid transport in a glutamine-deprived human neuroblastoma cell line. Biochim Biophys Acta 1525(1-2): 118-124, 2001
  • Wasa M, Wang HS, Okada A: Characterization of L-glutamine transport by a human neuroblastoma cell line. Am J Physiol-Cell Physiol 282(6): C1246-C1253, 2002
  • Wasa M, Wang H.S., Shimizu Y, Okada A: Amino acid transport is down-regulated in ischemic human intestinal epithelial cells. Biochim Biophys Acta 1670(1): 49-55, 2004
  • Wasa M, Soh H, Shimizu Y, Fukuzawa M: Glutamine stimulates amino acid transport during ischemia-reperfusion in human intestinal epithelial cells. J Surg Res 123(1): 75-81, 2005
  • Nose S, Wasa M, Tazuke Y, Owari M, Fukuzawa M. Cisplatin up-regulates glutamine transport in human intestinal epithelial cells: The protective mechanism of glutamine on intestinal mucosa after chemotherapy. JPEN-J Parenter Enteral Nutr 34(5):530-537, 2010
  • Tsujimoto T, Shimizu K, Hata N, Takagi T, Uejima E, Ogura H, Wasa M, Shimazu T. Both high and low plasma glutamine levels predict mortality in critically ill patients. Surg Today , 47(11): 1331-1338,2017